Stockholders' Equity - Summary of Stock Option Activity (Details)	12 Months Ended
	Dec. 31, 2022 USD ($) $ / shares shares
Number of shares
Number of shares, Outstanding, beginning balance | shares	5,090,377
Number of shares, Granted | shares	2,222,866
Number of shares, Exercised | shares	(340,149)
Number of shares, Forfeited | shares	(317,942)
Number of shares, Expired | shares	(37,424)
Number of shares, Outstanding, ending balance | shares	6,617,728
Number of shares, Vested and expected to vest | shares	6,617,728
Number of shares, Exercisable | shares	3,470,813
Weighted average exercise price
Weighted average exercise price, Outstanding, beginning balance | $ / shares	$ 28.89
Weighted average exercise price, Granted | $ / shares	38.62
Weighted average exercise price, Exercised | $ / shares	18.38
Weighted average exercise price, Forfeited | $ / shares	39.50
Weighted average exercise price, Expired | $ / shares	54.76
Weighted average exercise price, Outstanding, ending balance | $ / shares	31.80
Weighted average exercise price, Vested and expected to vest | $ / shares	31.80
Weighted average exercise price, Exercisable | $ / shares	$ 21.43
Weighted average contractual term
Weighted average contractual term, Outstanding	7 years 3 months 18 days
Weighted average contractual term, Vested and expected to vest	7 years 3 months 18 days
Weighted average contractual term, Exercisable	5 years 9 months 18 days
Aggregate intrinsic value
Aggregate intrinsic value, Outstanding | $	$ 300,653,467
Aggregate intrinsic value, Vested and expected to vest | $	300,653,467
Aggregate intrinsic value, Exercisable | $	$ 193,768,216