Consolidated Statements of Stockholders' Equity - USD ($)	Total	License Agreement	Common Stock	Common Stock License Agreement	Additional Paid-in Capital	Additional Paid-in Capital License Agreement	Accumulated Deficit
Beginning balance at Dec. 31, 2019	$ 178,722,389		$ 3,693		$ 354,614,189		$ (175,895,493)
Balance (in shares) at Dec. 31, 2019			36,933,217
Stock-based compensation	14,756,206				14,756,206
Issuance of common stock upon exercise of options	1,049,849		$ 13		1,049,836
Issuance of common stock upon exercise of options (in shares)			127,778
Exercise of warrants	6		$ 6
Exercise of warrants (in shares)			63,831
Issuance of warrants upon debt financing	884,216				884,216
Issuance of common stock upon financing	14,125,506	$ 7,155,337	$ 17	$ 8	14,125,489	$ 7,155,329
Issuance of common stock upon financing (in shares)			167,243	82,019
Net loss	(102,900,600)						(102,900,600)
Ending balance at Dec. 31, 2020	113,792,909		$ 3,737		392,585,265		(278,796,093)
Balance (in shares) at Dec. 31, 2020			37,374,088
Stock-based compensation	20,801,380				20,801,380
Issuance of common stock upon exercise of options	4,402,400		$ 33		4,402,367
Issuance of common stock upon exercise of options (in shares)			326,219
Issuance of common stock upon vesting of RSUs	1		$ 1
Issuance of common stock upon vesting of RSUs (in shares)			6,191
Issuance of common stock upon financing	7,212,367		$ 11		7,212,356
Issuance of common stock upon financing (in shares)			110,296
Shares tendered for withholding taxes	(175,713)		$ 0		(175,713)
Net loss	(130,402,992)		0				(130,402,992)
Ending balance at Dec. 31, 2021	$ 15,630,352		$ 3,782		424,825,655		(409,199,085)
Balance (in shares) at Dec. 31, 2021	37,816,794		37,816,794
Stock-based compensation	$ 37,726,158				37,726,158
Issuance of common stock upon exercise of options	$ 6,251,173		$ 34		6,251,139
Issuance of common stock upon exercise of options (in shares)	340,149		340,149
Exercise of warrants	$ 826,153				826,153
Issuance of common stock upon vesting of RSUs	0		$ 2		(2)
Issuance of common stock upon vesting of RSUs (in shares)			21,214
Issuance of common stock upon financing	236,788,056		$ 532		236,787,524
Issuance of common stock upon financing (in shares)			5,320,460
Shares tendered for withholding taxes	(531,832)				(531,832)
Net loss	(187,133,651)						(187,133,651)
Ending balance at Dec. 31, 2022	$ 109,556,409		$ 4,350		$ 705,884,795		$ (596,332,736)
Balance (in shares) at Dec. 31, 2022	43,498,617		43,498,617