Stockholders' Equity - Summary of Stock Option Activity (Details)	3 Months Ended
	Mar. 31, 2022 USD ($) $ / shares shares
Number of shares
Number of shares, Outstanding, beginning balance | shares	5,090,377
Number of shares, Granted | shares	1,223,019
Number of shares, Exercised | shares	(18,015)
Number of shares, Forfeited | shares	(67,139)
Number of shares, Expired | shares	(9,212)
Number of shares, Outstanding, ending balance | shares	6,219,030
Number of shares, Vested and expected to vest | shares	6,219,030
Number of shares, Exercisable | shares	2,932,835
Weighted average exercise price
Weighted average exercise price, Outstanding, beginning balance | $ / shares	$ 28.89
Weighted average exercise price, Granted | $ / shares	30.05
Weighted average exercise price, Exercised | $ / shares	10.08
Weighted average exercise price, Forfeited | $ / shares	43.83
Weighted average exercise price, Expired | $ / shares	53.10
Weighted average exercise price, Outstanding, ending balance | $ / shares	28.98
Weighted average exercise price, Vested and expected to vest | $ / shares	28.98
Weighted average exercise price, Exercisable | $ / shares	$ 15.85
Weighted average contractual term
Weighted average contractual term, Outstanding	7 years 7 months 6 days
Weighted average contractual term, Vested and expected to vest	7 years 7 months 6 days
Weighted average contractual term, Exercisable	5 years 8 months 12 days
Aggregate intrinsic value
Aggregate intrinsic value, Outstanding | $	$ 106,188,389
Aggregate intrinsic value, Vested and expected to vest | $	106,188,389
Aggregate intrinsic value, Exercisable | $	$ 82,434,018