Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Cash flows from operating activities
Net loss	$ (130,402,992)	$ (102,900,600)	$ (68,345,186)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	20,801,380	14,756,206	6,115,160
Non-cash research and development license expense		7,155,337
Amortization of debt discount	1,077,015	786,750	649,993
Loss on extinguishment of debt		1,247,012
Amortization of operating lease right-of-use asset	1,079,313	53,854
Change in operating lease liability	(1,181,620)	8,967
Depreciation	76,350	23,864	37,330
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	103,087	264,722	833,265
Other assets	(5,535)	(177,500)	(27,530)
Accounts payable	(354,693)	2,560,697	7,256,080
Accrued expenses and other current liabilities	581,931	(2,235,878)	7,105,829
Net cash used in operating activities	(108,225,764)	(78,456,569)	(46,375,059)
Cash flows from investing activities
Purchases of equipment	(307,549)	(45,891)	(16,121)
Net cash used in investing activities	(307,549)	(45,891)	(16,121)
Cash flows from financing activities
Proceeds from issuance of term loan		50,000,000	20,000,000
Payment of debt issuance costs	(309,340)	(1,102,609)
Repayment of principal on term loan		(21,660,000)	(7,238,889)
Proceeds from issuance of common stock upon financing, net	7,212,367	14,125,506	238,233,817
Proceeds from issuance of common stock upon exercise of warrants			249,836
Proceeds from issuance of common stock upon exercise of options	4,402,400	1,049,849	1,143,841
Payments of tax withholdings on stock award	(175,713)
Net cash provided by financing activities	11,129,714	42,412,746	252,388,605
Net (decrease) increase in cash	(97,403,599)	(36,089,714)	205,997,425
Cash at beginning of period	183,876,453	219,966,167	13,968,742
Cash at end of period	86,472,854	183,876,453	219,966,167
Supplemental disclosures of cash flow information:
Interest paid	$ 4,625,208	2,097,292	1,287,506
Operating lease right-of-use asset obtained in exchange for operating lease liability		1,793,328
Supplemental disclosures of non-cash financing activity:
Issuance of warrants in connection with debt financing		$ 884,216	$ 387,000