Net Loss per Common Share - Computation of Basic and Diluted Net Loss per Common Share (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Basic and diluted net loss per common share:
Net loss	$ (130,402,992)	$ (102,900,600)	$ (68,345,186)
Weighted average common shares outstanding, basic and diluted	37,618,599	37,206,928	34,020,257
Net loss per common share, basic and diluted	$ (3.47)	$ (2.77)	$ (2.01)