Net Loss per Common Share (Tables)

12 Months Ended

Dec. 31, 2021

Earnings Per Share [Abstract]

Computation of Basic and Diluted Net Loss per Common Share

The following table sets forth the computation of basic and diluted net loss per common share:

	Year ended December 31,
	2021			2020			2019
Basic and diluted net loss per common share:
Net loss	$	(130,402,992	)	$	(102,900,600	)	$	(68,345,186	)
Weighted average common shares outstanding—basic and diluted		37,618,599			37,206,928			34,020,257
Net loss per common share—basic and diluted	$	(3.47	)	$	(2.77	)	$	(2.01	)

Schedule of Potentially Dilutive Securities

The following potentially dilutive securities outstanding at December 31, 2021, 2020, and 2019 have been excluded from the computation of diluted weighted average shares outstanding, as they would be anti‑dilutive:

	December 31,
	2021		2020		2019
Stock options		5,090,377		3,733,916		3,458,447
Restricted stock units		326,625		136,067		—
Warrants		15,541		15,541		69,656
Total		5,432,543		3,885,524		3,528,103