X0306 4 2015-05-22 0 0001070081 PTC THERAPEUTICS, INC. PTCT 0001579397 Kovacs Shane William Charles C/O PTC THERAPEUTICS, INC. 100 CORPORATE COURT SOUTH PLAINFIELD NJ 07080 0 1 0 0 Chief Financial Officer Common Stock 2015-05-22 4 M 0 60375 10.85 A 72725 D Common Stock 2015-05-22 4 M 0 18616 27.05 A 91341 D Common Stock 2015-05-22 4 S 0 64041 55.26 D 27300 D Common Stock 2015-05-22 4 S 0 18450 55.93 D 8850 D Stock Option (Right to Buy) 10.85 2015-05-22 4 M 0 60375 0 D 2023-05-21 Common Stock 60375 65625 D Stock Option (Right to Buy) 27.05 2015-05-22 4 M 0 18616 0 D 2024-01-27 Common Stock 18616 46384 D Stock Option (Right to Buy) 51.00 2025-01-01 Common Stock 85600 85600 D The transactions reported in this Form 4 were effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person for the primary purposes of covering tax obligations associated with a restricted stock vesting event and diversification. This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $54.73 to $55.72 per share. The reporting person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $55.73 to $56.48 per share. The reporting person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. This option award was granted on May 22, 2013, with 25% of the shares underlying the option vested on May 22, 2014, and an additional 2.083% of the original number of shares underlying the option vesting on a monthly basis thereafter, beginning on June 30, 2014. This option award was granted on January 28, 2014, with 25% of the shares underlying the option vested on January 1, 2015, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 1, 2015. This option award was granted on January 2, 2015, with 25% of the shares underlying the option vesting on January 1, 2016, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 1, 2016. /s/ Colleen Diver Johnson, attorney-in-fact 2015-05-22