The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC. COM 00287Y109 92,493 1,580,000 SH   SOLE   1,580,000 0 0
AEGERION PHARMACEUTICALS INC COM 00767E102 42,852 1,637,455 SH   SOLE   1,637,455 0 0
AMGEN INC COM 031162100 50,832 318,000 SH   SOLE   318,000 0 0
ANI PHARMACEUTICALS INC COM 00182C103 1,939 31,000 SH   SOLE   31,000 0 0
APRICUS BIOSCIENCES INC COM 03832V109 12,201 6,524,505 SH   SOLE   6,524,505 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 105,884 12,850,000 SH   SOLE   12,850,000 0 0
AVEO PHARMACEUTICALS INC COM 053588109 3,728 2,570,759 SH   SOLE   2,570,759 0 0
ELEVEN BIOTHERAPEUTICS INC. COM 286221106 368 41,200 SH   SOLE   41,200 0 0
FLAMEL TECHNOLOGIES SA SPONSORED ADR 338488109 15,733 875,000 SH   SOLE   875,000 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 8,597 360,000 SH   SOLE   360,000 0 0
KINDRED BIOSCIENCES INC COM 494577109 4,920 689,091 SH   SOLE   689,091 0 0
MEDICINES CO COM 584688105 34,047 1,215,100 SH   SOLE   1,215,100 0 0
MERCK & CO INC NEW COM 58933Y105 22,992 400,000 SH   SOLE   400,000 0 0
QUEST DIAGNOSTICS INC COM 74834L100 59,559 775,000 SH   SOLE   775,000 0 0
REPROS THERAPEUTICS INC COM NEW 76028H209 9,727 1,132,367 SH   SOLE   1,132,367 0 0
TARGACEPT INC COM 87611R306 1,871 630,000 SH   SOLE   630,000 0 0
VIVUS INC COM 928551100 6,332 2,573,943 SH   SOLE   2,573,943 0 0