The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AGILENT TECHNOLOGIES INC. COM 00846U101 18,832 460,000 SH   SOLE   460,000 0 0
AMGEN INC COM 031162100 50,654 318,000 SH   SOLE   318,000 0 0
ANI PHARMACEUTICALS INC COM 00182C103 1,748 31,000 SH   SOLE   31,000 0 0
APRICUS BIOSCIENCES INC COM 03832V109 1,030 1,030,000 SH   SOLE   1,030,000 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 88,280 12,850,000 SH   SOLE   12,850,000 0 0
AVEO PHARMACEUTICALS INC COM 053588109 2,160 2,570,759 SH   SOLE   2,570,759 0 0
BIO-REFERENCE LABS INC COM $.01 NEW 09057G602 12,539 390,270 SH   SOLE   390,270 0 0
CYCLACEL PHARMACEUTICALS INC. COM NEW 23254L306 263 376,000 SH   SOLE   376,000 0 0
ELEVEN BIOTHERAPEUTICS INC. COM 286221106 489 41,200 SH   SOLE   41,200 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 6,354 360,000 SH   SOLE   360,000 0 0
KINDRED BIOSCIENCES INC COM 494577109 5,134 689,091 SH   SOLE   689,091 0 0
MERCK & CO INC NEW COM 58933Y105 22,716 400,000 SH   SOLE   400,000 0 0
QUEST DIAGNOSTICS INC COM 74834L100 51,972 775,000 SH   SOLE   775,000 0 0
REPROS THERAPEUTICS INC COM NEW 76028H209 11,290 1,132,367 SH   SOLE   1,132,367 0 0
TARGACEPT INC COM 87611R306 1,657 630,000 SH   SOLE   630,000 0 0
VIVUS INC COM 928551100 7,413 2,573,943 SH   SOLE   2,573,943 0 0