The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AMGEN INC COM 031162100 5,327 45,000 SH   SOLE   45,000 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 76,440 12,000,000 SH   SOLE   12,000,000 0 0
AVEO PHARMACEUTICALS INC COM 053588109 4,704 2,570,759 SH   SOLE   2,570,759 0 0
BIO-REFERENCE LABS INC COM $.01 NEW 09057G602 38,711 1,280,984 SH   SOLE   1,280,984 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 4,522 105,000 SH   SOLE   105,000 0 0
IDENIX PHARMACEUTICALS INC COM 45166R204 48,200 2,000,000 SH   SOLE   2,000,000 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 3,628 215,202 SH   SOLE   215,202 0 0
KINDRED BIOSCIENCES INC COM 494577109 4,252 228,126 SH   SOLE   228,126 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 3,873 37,824 SH   SOLE   37,824 0 0
MERCK & CO INC NEW COM 58933Y105 23,140 400,000 SH   SOLE   400,000 0 0
ONCONOVA THERAPEUTICS INC COM 68232V108 1,901 350,000 SH   SOLE   350,000 0 0
QUEST DIAGNOSTICS INC COM 74834L100 45,485 775,000 SH   SOLE   775,000 0 0
REPROS THERAPEUTICS INC COM NEW 76028H209 17,358 1,003,367 SH   SOLE   1,003,367 0 0
TARGACEPT INC COM 87611R306 2,841 630,000 SH   SOLE   630,000 0 0
VIVUS INC COM 928551100 13,693 2,573,943 SH   SOLE   2,573,943 0 0