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Condensed Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Cash flows from operating activities    
Net loss $ (20,737) $ (28,796)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 12 15
Stock-based compensation expense 2,396 2,474
Amortization of premiums and accretion of discounts on marketable securities, net 25 (588)
Change in fair value of embedded derivatives (460) (190)
Amortization of right-of-use asset 34 30
Realized gain on marketable securities (6) (3)
Noncash interest expense 346 299
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 691 950
Other long-term assets 0 16
Accounts payable 1,047 (4,592)
Accrued clinical trial expenses (2,433) (3,796)
Accrued expenses and other liabilities (5,043) 60
Net cash used in operating activities (24,128) (34,121)
Cash flows from investing activities    
Purchases of marketable securities (40,823) (35,048)
Proceeds from maturities and sales of marketable securities 27,016 63,816
Purchases of property and equipment 0 (79)
Net cash (used in) provided by investing activities (13,807) 28,689
Cash flows from financing activities    
Proceeds from private placement, net of offering costs 35,746 0
Proceeds from exercise of stock options 145 37
Repurchase of common shares to pay employee withholding taxes (149) (73)
Net cash provided by (used in) financing activities 35,742 (36)
Net change in cash and cash equivalents and restricted cash (2,193) (5,468)
Cash and cash equivalents and restricted cash at the beginning of the period 54,220 35,859
Cash and cash equivalents and restricted cash at the end of the period 52,027 30,391
Supplemental disclosure of cash flow information    
Cash paid for income taxes 0 0
Cash paid for interest 723 724
Supplemental disclosure of noncash financing activities    
Offering costs included in accounts payable 54 0
Offering costs included in accrued expenses and other current liabilities $ 239 $ 0