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Share-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Assumptions Used for Valuation of Fair Value of Stock Options
The Black-Scholes option-pricing model was used to estimate the fair value of stock options granted during the year ended December 31, 2021 with the following weighted average assumptions: 

Risk-free interest rate
  0.4% – 1.3%
Expected term (in years)
   5.3 – 6.1
Expected volatility
   90%
Expected dividend yield
   0%
Summary of Assumptions Used for Valuation of Fair Value of Stock
As of December 31, 2020, management, with the assistance of an independent third-party valuation firm, estimated the fair value of a share of common stock to be $0.83 utilizing the following assumptions: 
 
Risk-free interest rate
  
0.13
%
Expected time to liquidity event (in years)
   2.0
Expected volatility
   90%
Expected dividend yield
   0%
Summary of Stock Option Activity
The following table reflects summarized stock option activity: 
 
   
Stock Options
   
Weighted Average
Exercise Price
   
Weighted Average
Remaining
Contractual Life
(in years)
   
Aggregate Intrinsic
Value (in thousands)
 
Outstanding at December 31, 2020
    1,001,517     $ 1.13                  
Granted
    2,839,284       2.99                  
Exercised
    (5,183     2.85                  
Outstanding at December 31, 2021
    3,835,618     $ 2.51       8.5     $ 19,458  
Vested and exercisable at December 31, 2021
    1,004,510     $ 1.56       6.9     $ 5,523  
Summary of Share-Based Compensation Expense Related to Stock Options
The Company recorded stock-based compensation expense related to stock options in the following expense categories of its statements of operations for the periods shown (in thousands):
    
Year Ended
December 31,
 
    
2021
    
2020
 
General and administrative
   $ 690      $ 103  
Research and development
     232        51  
Total stock-based compensation
   $ 922      $ 154