Income Taxes - Schedule of the Components of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Deferred tax assets:
Net operating losses carryforwards	$ 491,136	$ 422,990
Net operating losses - foreign	3,842	0
Capitalized research and development costs	134,447	118,340
Property, equipment and intangible assets	18,175	14,429
Accruals and reserves	47,906	42,043
Research and development credits	80,954	71,330
Stock-based compensation	4,642	12,923
Lease liabilities	51,852	49,538
Other	7,010	2,379
Total deferred tax assets	839,964	733,972
Deferred tax liabilities:
IPR&D	(4,791)	0
Right-of-use asset	(39,964)	(36,426)
Other	(225)	(313)
Total deferred tax liabilities	(44,980)	(36,739)
Less: valuation allowance	(788,795)	(696,473)
Net deferred tax assets	$ 6,189	$ 760