Common Stock - Schedule of Common Stock Reserved for Future Issuance (Details) - shares	Dec. 31, 2025	Dec. 31, 2024
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	28,158,912	27,147,526
Shares underlying outstanding stock options
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	4,548,494	4,631,750
Shares underlying unvested restricted stock units
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	6,315,213	7,020,251
Shares underlying unvested performance-based restricted stock units
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	1,280,838	1,290,684
Shares available for issuance under the 2018 Incentive Award Plan
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	9,811,870	8,079,498
Shares available for issuance under the 2018 Employee Stock Purchase Plan
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	2,833,178	2,208,577
Shares available for issuance under the 2023 Employment Inducement Incentive Award Plan
Class of Stock [Line Items]
Common stock, shares reserved for future issuance (in shares)	3,369,319	3,916,766