Condensed Consolidated Statements of Stockholders’ (Deficit) Equity (unaudited) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2022		102,619,383
Beginning balance at Dec. 31, 2022	$ 60,180	$ 1	$ 1,742,114	$ (19,522)	$ (1,662,413)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in public offering, net of offering costs (in shares)		14,375,000
Issuance of common stock in public offering, net of offering costs	381,369		381,369
Issuance of common stock upon exercise of stock options (in shares)		40,868
Issuance of common stock upon exercise of stock options	290		290
Vesting of restricted stock units (in shares)		515,123
Common stock issued under employee stock purchase plan (in shares)		298,781
Common stock issued under employee stock purchase plan	6,697		6,697
Taxes paid related to net share settlement of restricted stock units	(8,112)		(8,112)
Stock-based compensation	66,439		66,439
Other comprehensive income	13,842			13,842
Net loss	(292,406)				(292,406)
Ending balance (in shares) at Sep. 30, 2023		117,849,155
Ending balance at Sep. 30, 2023	228,299	$ 1	2,188,797	(5,680)	(1,954,819)
Beginning balance (in shares) at Jun. 30, 2023		117,662,134
Beginning balance at Jun. 30, 2023	292,726	$ 1	2,169,911	(8,469)	(1,868,717)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		8,989
Issuance of common stock upon exercise of stock options	70		70
Vesting of restricted stock units (in shares)		178,032
Taxes paid related to net share settlement of restricted stock units	(3,003)		(3,003)
Stock-based compensation	21,819		21,819
Other comprehensive income	2,789			2,789
Net loss	(86,102)				(86,102)
Ending balance (in shares) at Sep. 30, 2023		117,849,155
Ending balance at Sep. 30, 2023	228,299	$ 1	2,188,797	(5,680)	(1,954,819)
Beginning balance (in shares) at Dec. 31, 2023		121,629,861
Beginning balance at Dec. 31, 2023	$ 158,684	$ 1	2,304,220	(3,675)	(2,141,862)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)	581,495	581,495
Issuance of common stock upon exercise of stock options	$ 2,597		2,597
Vesting of restricted stock units (in shares)		575,236
Common stock issued under employee stock purchase plan (in shares)		371,826
Common stock issued under employee stock purchase plan	7,212		7,212
Taxes paid related to net share settlement of restricted stock units	(7,658)		(7,658)
Stock-based compensation	104,045		104,045
Other comprehensive income	391			391
Net loss	(325,367)				(325,367)
Ending balance (in shares) at Sep. 30, 2024		123,158,418
Ending balance at Sep. 30, 2024	(60,096)	$ 1	2,410,416	(3,284)	(2,467,229)
Beginning balance (in shares) at Jun. 30, 2024		122,969,580
Beginning balance at Jun. 30, 2024	(1,613)	$ 1	2,363,501	(5,640)	(2,359,475)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		4,143
Issuance of common stock upon exercise of stock options	20		20
Vesting of restricted stock units (in shares)		184,695
Taxes paid related to net share settlement of restricted stock units	(2,874)		(2,874)
Stock-based compensation	49,769		49,769
Other comprehensive income	2,356			2,356
Net loss	(107,754)				(107,754)
Ending balance (in shares) at Sep. 30, 2024		123,158,418
Ending balance at Sep. 30, 2024	$ (60,096)	$ 1	$ 2,410,416	$ (3,284)	$ (2,467,229)