Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
OPERATING ACTIVITIES:
Net loss	$ (479,449)	$ (654,588)	$ (384,770)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	42,881	35,962	22,271
Operating lease costs	29,699	28,585	24,661
Contingent consideration	110	4,305	2,380
Stock-based compensation	90,759	94,685	151,449
Amortization of debt issuance costs	2,575	2,569	2,564
Amortization of (discount) premium on marketable debt securities	(13,552)	4,595	12,849
Unrealized (gains) losses on marketable equity securities	(79,710)	7,793	0
Impairment of non-marketable equity securities and other related assets	29,054	5,261	0
Fair value adjustments of noncontrolling interest liability	0	99,785	0
Other	(1,182)	21	47
Cash effect of changes in operating assets and liabilities:
Accounts receivable, net	8,378	375	(44,353)
Inventory, net	(10,350)	(20,926)	(7,957)
Prepaid expenses and other current assets, net	(4,332)	20,444	(35,753)
Other assets, net	1,298	11,698	(4,182)
Accounts payable and accrued liabilities	88,591	60,328	34,796
Operating lease liabilities	(31,478)	(20,228)	14,205
Deferred revenue	1,733	9,873	2,776
Net cash used in operating activities	(324,975)	(309,463)	(209,017)
INVESTING ACTIVITIES:
Purchase of marketable debt securities	(629,902)	(303,757)	(900,808)
Maturity of marketable debt securities	1,494,700	555,000	952,110
Purchase of non-marketable equity securities and other related assets	(5,593)	(23,966)	(39,422)
Purchase of property and equipment	(20,486)	(77,461)	(75,035)
Other	1,531	0	0
Net cash provided by (used in) investing activities	840,250	149,816	(63,155)
FINANCING ACTIVITIES:
Proceeds from issuance of common stock under employee stock purchase plan	10,154	9,316	9,753
Proceeds from issuance of common stock upon exercise of stock options	405	2,625	8,112
Taxes paid related to net share settlement of restricted stock units	(11,197)	(7,878)	(83,759)
Proceeds from equity offerings	493,116	0	0
Payment of equity offering costs	(21,131)	0	0
Joint Venture Acquisition	0	(177,785)	0
Tender offer issued in connection with the Joint Venture Acquisition and acquisition related costs	0	(14,235)	0
Other	6,028	(1,136)	(930)
Net cash provided by (used in) financing activities	477,375	(189,093)	(66,824)
Net effect of foreign exchange rate changes on cash, cash equivalents and restricted cash	(911)	(1,600)	(1,693)
Net increase (decrease) in cash, cash equivalents and restricted cash	991,739	(350,340)	(340,689)
Cash, cash equivalents and restricted cash – Beginning of period	141,948	492,288	832,977
Cash, cash equivalents and restricted cash – End of period	1,133,687	141,948	492,288
Supplemental Disclosures of Cash Flow Information:
Cash paid for income taxes	1,969	1,331	393
Supplemental Disclosures of Noncash Investing and Financing Activities:
Operating lease liabilities arising from obtaining right-of-use assets	5,015	4,073	171,382
Purchase of property and equipment included in accounts payable and accrued liabilities	5,279	8,291	8,892
Reclassification of redeemable noncontrolling interest to noncontrolling interest liability	0	0	78,000
Reconciliation of cash, cash equivalents and restricted cash:
Cash and cash equivalents	1,133,537	141,647	492,202
Restricted cash – included in other assets, net	150	301	86
Total cash, cash equivalents and restricted cash	$ 1,133,687	$ 141,948	$ 492,288