Accrued Liabilities and Other Liabilities - Summary (Details) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Accrued liabilities:
Accrued clinical expense	$ 41,584	$ 37,604
Accrued manufacturing expense	6,114	6,605
Accrued development expense	4,629	20,107
Accrued compensation and benefits	34,932	40,208
Accrued commercial expense	4,547	3,941
Accrued royalty expense	869	0
Accrued adjustments to product revenue	1,922	152
Other accrued expenses	4,925	4,126
Lease liability (current)	7,961	7,844
Total accrued liabilities	107,483	120,587
Other liabilities	$ 3,380	$ 3,022