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Shareholders' Equity (Tables)
6 Months Ended
Jun. 30, 2023
Share-Based Payment Arrangement [Abstract]  
Schedule of Employee Service Share-based Compensation Allocation
Total share-based compensation expense included in the condensed consolidated statements of operations and comprehensive loss consisted of the following (in thousands):

Three Months Ended June 30,
Six Months Ended June 30,
2023202220232022
Research and development expense$18,399 $22,807 $43,038 $49,067 
Selling, general and administrative expense21,000 15,877 43,322 32,522 
$39,399 $38,684 $86,360 $81,589