CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Current assets
Cash and cash equivalents	$ 129,866	$ 235,260
Short-term investments	649,568	848,577
Accounts receivable, net	10,523	865
Inventory	8,644	3,020
Other current assets	20,316	21,239
Total current assets	818,917	1,108,961
Property and equipment, net	16,867	17,540
Intangible asset, net	14,397	14,914
Long-term investment	4,565	3,465
Right-of-use asset	35,431	36,122
Other long-term assets	24,866	21,645
Total assets	915,043	1,202,647
Current liabilities
Accounts payable	32,507	38,861
Accrued liabilities	107,483	120,587
Total current liabilities	139,990	159,448
Lease liability	42,722	43,661
Other liabilities	3,380	3,022
Total liabilities	186,092	206,131
Commitments and contingencies (see Note 11)
Shareholders' equity
Preferred stock, $0.001 par value, 10,000,000 shares authorized; none issued and outstanding at both June 30, 2023 and December 31, 2022	0	0
Common stock, $0.001 par value; 100,000,000 authorized; 58,339,232 and 57,854,559 issued and outstanding at June 30, 2023 and December 31, 2022, respectively	58	58
Additional paid-in capital	3,544,996	3,453,066
Accumulated other comprehensive loss	(1,715)	(3,719)
Accumulated deficit	(2,814,388)	(2,452,889)
Total shareholders' equity	728,951	996,516
Total liabilities and shareholders' equity	$ 915,043	$ 1,202,647