CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Total revenue	$ 7,167	$ 709
Revenue
Total revenue	7,167	709
Operating expenses
Cost of product revenue	558	0
Cost of product revenue - intangible asset amortization	259	0
Research and development	126,683	130,976
Selling, general and administrative	73,490	53,951
Total operating expenses	200,990	184,927
Loss from operations	(193,823)	(184,218)
Other income (expense), net	9,237	(4,168)
Net loss	(184,586)	(188,386)
Foreign currency translation adjustment	(31)	0
Unrealized gain (loss) on available-for-sale investments	2,043	(4,802)
Comprehensive loss	$ (182,574)	$ (193,188)
Basic net loss per share (USD per share)	$ (3.18)	$ (3.40)
Diluted net loss per share (USD per share)	$ (3.18)	$ (3.40)
Weighted average common shares outstanding, basic (shares)	58,031,642	55,468,851
Weighted average common shares outstanding, diluted (shares)	58,031,642	55,468,851
Product Revenue
Total revenue	$ 6,291	$ 0
Revenue
Total revenue	6,291	0
License and Collaboration Revenue
Total revenue	876	709
Revenue
Total revenue	$ 876	$ 709