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Shareholders' Equity (Tables)
3 Months Ended
Mar. 31, 2023
Share-Based Payment Arrangement [Abstract]  
Schedule of Employee Service Share-based Compensation Allocation
Total share-based compensation expense included in the condensed consolidated statements of operations and comprehensive loss consisted of the following (in thousands):
Three Months Ended March 31,
20232022
Research and development expense$24,639 $26,260 
Selling, general and administrative expense22,322 16,645 
$46,961 $42,905