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Shareholders' Equity - Narrative (Details) - USD ($)
$ / shares in Units, $ in Millions
1 Months Ended 12 Months Ended
Nov. 30, 2021
Oct. 31, 2020
Jan. 31, 2020
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jul. 02, 2021
Jul. 02, 2020
Class of Stock [Line Items]                
Stock issued in transaction (shares) 3,448,275 4,585,706 3,538,462          
Sale price of common stock (USD per share) $ 145.00 $ 202.00 $ 97.50          
Proceeds from sale of common stock $ 474.7 $ 879.6 $ 324.0          
Common stock, par value (USD per share)       $ 0.001 $ 0.001   $ 0.001 $ 0.001
Aggregate offering price             $ 500.0 $ 200.0
Number of warrants exercised via cashless exercises (shares)       0 623,821 1,400,012    
Net exercise of warrants (shares)         623,814 1,400,000    
Exercise of warrants for cash (shares)           63,235    
At the Market Facility                
Class of Stock [Line Items]                
Stock issued in transaction (shares)       1,880,097        
Proceeds from sale of common stock       $ 155.0        
Excess Stock, Shares Issued       1,880,097