CONSOLIDATED BALANCE SHEETS - USD ($)	Dec. 31, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 235,260,000	$ 413,083,000
Short-term investments	848,577,000	1,078,257,000
Accounts receivable, net	865,000	0
Inventory	3,020,000	0
Other current assets	21,239,000	16,643,000
Total current assets	1,108,961,000	1,507,983,000
Property and equipment, net	17,540,000	15,824,000
Intangible asset, net	14,914,000	0
Long-term investment	3,465,000	8,218,000
Right-of-use asset	36,122,000	37,700,000
Other long-term assets	21,645,000	19,049,000
Total assets	1,202,647,000	1,588,754,000
Current liabilities
Accounts payable	38,861,000	35,163,000
Accrued liabilities	120,587,000	108,495,000
Total current liabilities	159,448,000	143,658,000
Lease liability	43,661,000
Other liabilities	3,022,000	2,179,000
Total liabilities	206,131,000	191,716,000
Commitments and contingencies (see Note 15)
Shareholders’ equity
Preferred stock, $0.001 par value, 10,000,000 shares authorized; none issued and outstanding at both December 31, 2022 and 2021	0	0
Common stock, $0.001 par value; 100,000,000 authorized; 57,854,559 and 55,356,904 issued and outstanding at December 31, 2022 and 2021, respectively	58,000	55,000
Additional paid-in capital	3,453,066,000	3,099,937,000
Accumulated other comprehensive (loss) income	(3,719,000)	9,068,000
Accumulated deficit	(2,452,889,000)	(1,712,022,000)
Total shareholders’ equity	996,516,000	1,397,038,000
Total liabilities and shareholders’ equity	$ 1,202,647,000	$ 1,588,754,000