CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue
Total revenue	$ 5,431	$ 71,793	$ 11,502	$ 71,793
Expenses
Research and development	131,076	116,109	390,391	354,755
General and administrative	60,798	35,183	168,977	93,144
Total operating expenses	191,874	151,292	559,368	447,899
Loss from operations	(186,443)	(79,499)	(547,866)	(376,106)
Other income (expense), net	13,136	2,744	9,728	(2,759)
Loss before income taxes	(173,307)	(76,755)	(538,138)	(378,865)
Income tax expense	254	3,299	254	3,299
Net loss	(173,561)	(80,054)	(538,392)	(382,164)
Foreign currency translation adjustment	(9,485)	0	(9,485)	0
Unrealized loss on available-for-sale investments	(1)	(6)	(5,712)	(164)
Comprehensive loss	$ (183,047)	$ (80,060)	$ (553,589)	$ (382,328)
Basic net loss per share (USD per share)	$ (3.09)	$ (1.55)	$ (9.66)	$ (7.45)
Diluted net loss per share (USD per share)	$ (3.09)	$ (1.55)	$ (9.66)	$ (7.45)
Weighted average common shares outstanding, basic (shares)	56,219,416	51,655,259	55,747,205	51,305,547
Weighted average common shares outstanding, diluted (shares)	56,219,416	51,655,259	55,747,205	51,305,547