Accrued Liabilities and Other Liabilities - Summary (Details) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Accrued liabilities:
Accrued clinical expense	$ 43,922	$ 29,038
Accrued manufacturing expense	8,617	34,153
Accrued development expense	8,023	10,910
Accrued compensation and benefits	22,049	25,845
Other accrued expenses	7,965	7,208
Lease liability (current)	4,302	1,341
Total accrued liabilities	94,878	108,495
Other liabilities	$ 2,816	$ 2,179