Income Taxes - Net Deferred Income Taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Tangible and intangible depreciable assets	$ 29,576	$ 32,180
Stock compensation	26,738	19,183
Provisions	5,740	2,510
Lease liability	9,916	8,800
Non-current investment	673	0
Net operating loss carryforward	299,204	182,536
Capital loss carryforward	89	114
Canada scientific research and experimental development expenditures	5,471	5,471
U.S. research and development tax credits	51,550	28,834
Total gross deferred tax assets	428,957	279,628
Less valuation allowance	(421,044)	(270,368)
Net deferred tax assets	7,913	9,260
Deferred tax liabilities:
Right-of-use asset	(7,913)	(8,377)
Non-current investment	0	(883)
Net deferred income taxes	$ 0	$ 0