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Share-Based Compensation - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
May 31, 2013
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Exercise price required percentage of fair market value 100.00%      
Award vesting period 4 years      
Intrinsic value of options exercised $ 91,100,000 $ 121,500,000 $ 38,600,000  
Cash received from exercise of stock options 28,000,000 45,900,000 8,500,000  
Fair value of options vested 58,300,000 52,100,000 20,400,000  
Compensation cost not yet recognized $ 88,800,000      
Compensation cost not yet recognized, period for recognition 1 year 3 months 18 days      
Capitalized costs $ 0 0 0  
Tax benefit from compensation expense $ 0 $ 0 $ 0  
Restricted stock units        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Award vesting period 4 years      
Fair value of options vested $ 17,400,000      
Compensation cost not yet recognized $ 67,600,000      
Compensation cost not yet recognized, period for recognition 2 years      
Performance Share Units (PSUs)        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Fair value of options vested $ 700,000      
Compensation cost not yet recognized $ 5,400,000      
Compensation cost not yet recognized, period for recognition 3 years 1 month 6 days      
2013 Plan        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Additional shares authorized (shares) 2,500,000      
Authorized amount for issuance (shares) 2,600,000      
Stock option contractual terms 10 years      
Stock authorized for purchase       $ 25,000
Purchase discount (as a percent)       85.00%
Stock reserved for future issuance (shares)       300,000
Issuance of common stock from ESPP (shares) 192,236      
Stock Option Plan        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Authorized amount for issuance (shares) 0      
Stock option contractual terms 7 years      
Inducement Plan        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding 121,574   417,343