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Shareholders' Equity - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Nov. 30, 2021
Oct. 31, 2020
Jan. 31, 2020
Jun. 30, 2019
Jan. 31, 2019
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Jul. 02, 2021
Jul. 02, 2020
Jun. 30, 2020
Equity [Abstract]                      
Stock issued in transaction (shares) 3,448,275 4,585,706 3,538,462 2,415,000 1,854,838            
Sale price of common stock (USD per share) $ 145.00 $ 202.00 $ 97.50   $ 62.00           $ 97.00
Proceeds from sale of common stock $ 474,700 $ 879,600 $ 324,000 $ 219,900 $ 107,900            
Common stock, par value (USD per share)           $ 0.001 $ 0.001   $ 0.001 $ 0.001  
Aggregate offering price                 $ 500,000 $ 200,000  
Proceeds from disgorgement of shareholders’ short-swing profits         $ 1,100 $ 0 $ 0 $ 1,050      
Number of warrants exercised via cashless exercises (shares)           623,821 1,400,012 2,125,033      
Net exercise of warrants (shares)           623,814 1,400,000        
Exercise of warrants for cash (shares)             63,235 2,125,000