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Fair Value Measurements (Tables)
12 Months Ended
Dec. 31, 2021
Fair Value Disclosures [Abstract]  
Schedule of Assets and Liabilities Measured at Fair Value on a Recurring Basis
The following table summarizes the assets and liabilities measured at fair value on a recurring basis (in thousands):

December 31, 2021
TotalLevel 1Level 2Level 3
Assets
Cash and cash equivalents:
Cash$19,347 $19,347 $— $— 
Money market funds393,736 393,736 — — 
Total cash and cash equivalents413,083 413,083 — — 
Short-term investments:
U.S. Treasury bills162,228 162,228 — — 
Corporate debt securities235,958 — 235,958 — 
Commercial paper621,979 — 621,979 — 
U.S. Agency bonds58,092 — 58,092 — 
Total short-term investments1,078,257 162,228 916,029 — 
Long-term investment:
ORIC Pharmaceuticals, Inc.8,218 — — 8,218 
Total$1,499,558 $575,311 $916,029 $8,218 
December 31, 2020
TotalLevel 1Level 2Level 3
Assets
Cash and cash equivalents:
Cash$20,398 $20,398 $— $— 
Money market funds865,164 865,164 — — 
Total cash and cash equivalents885,562 885,562 — — 
Short-term investments:
U.S. Treasury bills49,546 49,546 — — 
Corporate debt securities130,970 — 130,970 — 
Commercial paper240,765 — 240,765 — 
U.S. Agency bonds83,263 — 83,263 — 
Total short-term investments504,544 49,546 454,998 — 
Long-term investment:
ORIC Pharmaceuticals, Inc.15,629 — — 15,629 
Total$1,405,735 $935,108 $454,998 $15,629 
Schedule of Changes in Estimated Fair Value of Assets with Unobservable Inputs
The following table presents the changes in estimated fair value of the Company’s asset measured using significant unobservable inputs (Level 3) (in thousands):
December 31,
20212020
Balance - beginning of year$15,629 $— 
Additions— 11,424 
Change in fair value(7,411)4,205 
Balance - end of year$8,218 $15,629