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Investments
9 Months Ended
Sep. 30, 2021
Investments, Debt and Equity Securities [Abstract]  
Investments Investments
The following tables summarize the Company’s short-term investments (in thousands):
As of September 30, 2021
MaturityAmortized costGross unrealized gainsGross unrealized lossesEstimated fair value
Corporate debt securities
2 years or less
$215,349 $18 $(41)$215,326 
Commercial paper
1 year or less
528,373 81 (1)528,453 
U.S. Agency bonds
1 year or less
75,244 (1)75,252 
U.S. Treasury bills
2 years or less
83,723 22 (10)83,735 
Sovereign debt securities
1 year or less
9,030 — (2)9,028 
$911,719 $130 $(55)$911,794 

As of December 31, 2020
MaturityAmortized costGross unrealized gainsGross unrealized lossesEstimated fair value
Corporate debt securities
2 years or less
$130,814 $160 $(4)$130,970 
Commercial paper
1 year or less
240,725 58 (18)240,765 
U.S. Agency bonds
2 years or less
83,227 37 (1)83,263 
U.S. Treasury bills
2 years or less
49,539 10 (3)49,546 
$504,305 $265 $(26)$504,544 

The Company has classified all of its short-term investments as available-for-sale as the sale of such securities may be required prior to maturity to implement management strategies, and accordingly, carries these investments at fair value. As of September 30, 2021, and December 31, 2020, aggregated gross unrealized losses of available-for-sale investments were not material, and accordingly, no allowance for credit losses was recorded.

As of September 30, 2021 and December 31, 2020, the Company held 588,235 shares of ORIC Pharmaceuticals, Inc. (“ORIC”) common stock subject to certain transfer restrictions. The shares held by the Company are measured at fair value at each reporting period based on the closing price of ORIC’s common stock on the last trading day of each reporting period, adjusted for a discount for lack of marketability, with any unrealized gains and losses recorded in other income (expense), net on the Company’s condensed consolidated statements of operations and comprehensive loss. See Note 4 - Fair Value Measurements.