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Shareholders' Equity - Narrative (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Oct. 31, 2020
Jan. 31, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2020
Jul. 02, 2020
Class of Stock [Line Items]                
Stock issued in transaction (shares) 4,585,706 3,538,462            
Sale price of common stock (USD per share) $ 202.00 $ 97.50            
Proceeds from sale of stock $ 879,600,000 $ 324,000,000.0            
Common stock, par value (USD per share)     $ 0.001   $ 0.001   $ 0.001  
Stock issued pursuant to stock option exercises (shares)     224,129 323,789 537,032 820,310    
Proceeds from stock options exercised     $ 6,600,000 $ 8,700,000 $ 16,500,000 $ 23,900,000    
At the Market Facility                
Class of Stock [Line Items]                
Common stock, par value (USD per share)               $ 0.001
Aggregate offering price               $ 200,000,000.0