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Stockholders' Equity - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jun. 30, 2019
Jan. 31, 2019
Jun. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Stock issued in transaction (shares) 2,415,000 1,854,838 3,162,500        
Sale price of common stock (USD per share) $ 97.00 $ 62.00 $ 38.85        
Proceeds from sale of stock $ 219,900 $ 107,900 $ 130,700        
Exercise price of warrants (USD per share)     $ 0.001        
Stock issued pursuant to stock option exercises (shares)       91,257 202,601 424,144 716,409
Proceeds from stock options exercised       $ 1,100 $ 2,200 $ 5,400 $ 9,500
Proceeds from disgorgement of stockholders' short-swing profits   $ 1,100       $ 1,050 $ 0
Note Warrant              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Stock issued in transaction (shares)     421,650        
Sale price of common stock (USD per share)     $ 38.849        
Maximum              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Proportion of common stock owned (as a percent)             9.99%
Minimum              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Proportion of common stock owned (as a percent)             4.99%