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Summary of Significant Accounting Policies - Antidilutive Securities (Details) - shares
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities 12,313,878 14,032,786 12,810,852 13,404,840
Common stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities 2,487,135 2,215,086 2,398,467 1,835,879
Common stock warrants        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities 9,826,743 11,817,700 10,412,385 11,568,961