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Stockholders' Equity (Tables)
 9 Months Ended
Sep. 30, 2019
Share-based Payment Arrangement [Abstract]  
Schedule of Employee Service Share-based Compensation Allocation
Total share-based compensation expense by statement of operations and comprehensive loss classification is presented below (in thousands):
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2019
 
2018
 
2019
 
2018
Research and development expense
$
8,648

 
$
1,849

 
$
20,416

 
$
5,113

General and administrative expense
6,458

 
2,209

 
18,410

 
6,479

 
$
15,106

 
$
4,058

 
$
38,826

 
$
11,592