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Summary of Significant Accounting Policies - Antidilutive Securities (Details) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities 12,789,661 13,254,675 13,057,390 13,088,703
Common stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities 2,371,908 1,766,047 2,347,335 1,646,198
Common stock warrants        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities 10,417,753 11,488,628 10,710,055 11,442,505