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Property and Equipment, net (Details) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Property, Plant and Equipment [Line Items]      
Property and equipment, Gross $ 1,336   $ 1,256
Less: Accumulated depreciation (718)   (627)
Property and equipment, net 618   629
Depreciation 91 $ 101  
Computer equipment      
Property, Plant and Equipment [Line Items]      
Property and equipment, Gross 329   329
Office and other equipment      
Property, Plant and Equipment [Line Items]      
Property and equipment, Gross 301   301
Laboratory equipment      
Property, Plant and Equipment [Line Items]      
Property and equipment, Gross 643   563
Leasehold improvements      
Property, Plant and Equipment [Line Items]      
Property and equipment, Gross $ 63   $ 63