Property and Equipment, net (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 1,123		$ 1,061
Less: Accumulated depreciation	(586)		(447)
Property and equipment, net	537		614
Depreciation	139	$ 153
Computer equipment
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	329		329
Office and other equipment
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	301		256
Laboratory equipment
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	442		425
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 51		$ 51