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Other current assets (Details) - USD ($)
$ in Thousands
Jun. 30, 2016
Dec. 31, 2015
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]    
Prepaid expenses $ 928 $ 2,287
Security deposits and other receivables 516 551
Interest receivable 282 237
Other current assets 1,726 3,075
Deposits paid for research and development $ 2,400 $ 2,000