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Stockholders' Equity
3 Months Ended
Mar. 31, 2015
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Stockholders' Equity
Stockholders' Equity
Sale of Common Stock
    
In February 2015, the Company completed a follow-on offering whereby it issued an aggregate 2,587,500 shares of common stock at $20.00 per share. Proceeds from the follow-on offering, net of underwriting discounts, commissions and offering expenses, were $48.4 million.

Share-based Compensation
Total share-based compensation expense by operating statement classification is presented below (in thousands):
 
Three Months Ended March 31,
 
2015
 
2014
Research and development expense
$
808

 
$
488

General and administrative expense
1,508

 
458

 
$
2,316

 
$
946


During the three months ended March 31, 2015 and 2014, 22,166 and 23,307 shares were issued pursuant to stock option exercises generating net proceeds of $0.3 million for each period.