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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Operating activities    
Net loss for the year $ (20,286) $ (9,778)
Non-cash adjustments reconciling net loss to operating cash flows    
Depreciation of property and equipment 123 197
Write-off of property and equipment   77
Gain on disposal of property and equipment   (30)
Reversal of provision for lease resiliation   (52)
Stock-based compensation expense 2,009 940
License and up-front fees   (2,333)
Lease incentive 85 28
Changes in operating assets and liabilities    
Interest and other receivables (331) 150
Other current assets 45 (553)
Accounts payable and accrued liabilities 1,434 (353)
Change in provision for lease abandonment costs   (346)
Unbilled revenue   409
Cash flows used for operating activities (16,921) (11,644)
Investing activities    
Purchase of property and equipment (230) (110)
Purchases of marketable securities and term deposits (29,431) (44,670)
Security deposit (12) 61
Restricted cash equivalents and marketable securities 283 604
Disposal and maturities of marketable securities and term deposits 29,716 24,827
Proceeds from disposal of property and equipment   77
Cash flows provided by investing activities 326 (19,211)
Financing activities    
Issuance of common stock 20,966 29,032
Common stock issuance costs (1,080) (1,632)
Issuance of warrants 5,180 6,619
Warrant issuance costs (238) (372)
Costs of reorganization (15) (33)
Cash flows used for financing activities 24,813 33,614
Increase (decrease) in cash and cash equivalents 8,218 2,759
Effect of exchange rate changes on cash and cash equivalents 303 (278)
Cash and cash equivalents, beginning of period 9,882 7,401
Cash and cash equivalents, end of period 18,403 9,882
Income taxes paid 34  
Interest paid $ 6 $ 1