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COLLABORATION AGREEMENTS (Details)
12 Months Ended 1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 28 Months Ended 39 Months Ended 6 Months Ended 12 Months Ended 6 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 18 Months Ended 27 Months Ended 39 Months Ended 63 Months Ended 39 Months Ended 6 Months Ended 12 Months Ended 6 Months Ended 12 Months Ended 6 Months Ended 12 Months Ended
Dec. 31, 2012
USD ($)
Dec. 31, 2011
USD ($)
Oct. 31, 2003
Collaborative agreements
Taiho
USD ($)
Jun. 30, 2013
Collaborative agreements
Taiho
USD ($)
Jun. 30, 2012
Collaborative agreements
Taiho
USD ($)
Jun. 30, 2013
Collaborative agreements
Taiho
USD ($)
Jun. 30, 2012
Collaborative agreements
Taiho
USD ($)
Dec. 31, 2012
Collaborative agreements
Taiho
USD ($)
Dec. 31, 2011
Collaborative agreements
Taiho
USD ($)
Dec. 31, 2006
Collaborative agreements
Taiho
USD ($)
Jan. 31, 2006
Collaborative agreements
Taiho
USD ($)
Dec. 31, 2006
Collaborative agreements
Taiho
USD ($)
Jun. 30, 2013
Collaborative agreements
Taiho
Minimum
Dec. 31, 2012
Collaborative agreements
Taiho
Minimum
Jun. 30, 2013
Collaborative agreements
Taiho
Maximum
Dec. 31, 2012
Collaborative agreements
Taiho
Maximum
Mar. 25, 2008
Collaborative agreements
Otsuka
USD ($)
Oct. 31, 2009
Collaborative agreements
Otsuka
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
USD ($)
Jun. 30, 2012
Collaborative agreements
Otsuka
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
USD ($)
Jun. 30, 2012
Collaborative agreements
Otsuka
USD ($)
Dec. 31, 2012
Collaborative agreements
Otsuka
USD ($)
Sep. 25, 2009
Collaborative agreements
Otsuka
USD ($)
Jun. 30, 2010
Collaborative agreements
Otsuka
item
Jun. 30, 2011
Collaborative agreements
Otsuka
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
USD ($)
Dec. 31, 2011
Collaborative agreements
Otsuka
USD ($)
Dec. 31, 2010
Collaborative agreements
Otsuka
USD ($)
Oct. 31, 2009
Collaborative agreements
Otsuka
CAD
Jun. 30, 2011
Collaborative agreements
Otsuka
Development activities
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
Minimum
Dec. 31, 2012
Collaborative agreements
Otsuka
Minimum
Jun. 30, 2013
Collaborative agreements
Otsuka
Maximum
USD ($)
Dec. 31, 2012
Collaborative agreements
Otsuka
Maximum
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
Maximum
Development activities
USD ($)
Dec. 31, 2012
Collaborative agreements
Otsuka
Maximum
Development activities
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
Maximum
Regulatory approvals
USD ($)
Dec. 31, 2012
Collaborative agreements
Otsuka
Maximum
Regulatory approvals
USD ($)
Jun. 30, 2013
Collaborative agreements
Otsuka
Maximum
Achievement of certain sale goals
USD ($)
Dec. 31, 2012
Collaborative agreements
Otsuka
Maximum
Achievement of certain sale goals
USD ($)
Jun. 30, 2013
Collaborative agreements
EnVivo
USD ($)
Jun. 30, 2012
Collaborative agreements
EnVivo
USD ($)
Dec. 31, 2012
Collaborative agreements
EnVivo
USD ($)
Dec. 31, 2011
Collaborative agreements
EnVivo
USD ($)
Dec. 31, 2005
Collaborative agreements
EnVivo
USD ($)
Feb. 07, 2005
Collaborative agreements
EnVivo
USD ($)
Feb. 07, 2005
Collaborative agreements
EnVivo
CAD
Collaborative agreements                                                                                                
Contract research funding received     $ 3,900,000                                             $ 4,500,000                                       $ 600,000    
Proceeds from collaborators                   2,000,000 5,400,000 12,300,000         2,000,000             1,900,000   6,500,000 6,500,000       4,500,000                             1,100,000    
Amount received for equity investment     2,700,000                 2,700,000                           1,500,000                                            
Potential percentage reduction of royalty rate                         20.00% 20.00% 30.00% 30.00%                               40.00% 40.00% 50.00% 50.00%                          
Expiration period of agreement after the first sale           10 years   10 years                         12 years   12 years                                                  
Period of material breach considered for terminating the agreement by arbitrator           90 days   90 days                                                                       30 days        
Notice period for termination of agreement           30 days   30 days                         90 days   90 days                                                  
Period of breach of payment considered for terminating the agreement                                         30 days   30 days                                                  
Potential milestone payments                                                                   50,500,000 50,500,000 7,500,000 7,500,000 22,000,000 22,000,000 21,000,000 21,000,000              
Collaboration revenue   3,144,000   0 0 0 0 0 420,000                   0 0 0 0 0                                     0 0 0 0      
Research funding amount for initial period                                 1,900,000                                                              
Initial period for research funding                                 18 months                                                              
Number of occasions when collaboration period was extended                                                 3                                              
Up-front license fee unamortized balance                                                       1,700,000 1,700,000                                      
Equity investment in the Company's common stock 20,966,000 29,032,000 2,700,000                 2,700,000           1,500,000                 1,500,000                                          
Price per share of common stock issued as part of the collaboration agreement (in dollars per share)                                   $ 20.75                       21.3                                    
Percentage of premium on volume-weighted average price per share of common stock issued                                   20.00%                                                            
Period over which volume-weighted average closing price of the company's stock is used                                   5 days                                                            
License fee received     $ 1,000,000                           $ 2,000,000                                                         $ 500,000    
Warrants issued (in shares)                                                                                             1,050 1,050
Exercise price of warrants (in dollars per share)                                                                                             $ 171.55 214.3