EX-99.1 2 exhibit_99-1.htm EXHIBIT 99.1

Exhibit 99.1
Evogene Reports Second Quarter 2022 Financial Results
 
Conference call and webcast: today, August 31, 2022, 9:00 am ET
 
Rehovot, Israel – August 31, 2022 – Evogene Ltd. (Nasdaq: EVGN, TASE: EVGN), a leading computational biology company targeting to revolutionize life-science product discovery and development across multiple market segments, announced today its financial results for the second quarter ended June 30, 2022.
  
Mr. Ofer Haviv, Evogene's President and Chief Executive Officer, stated, “We are very pleased with the two recent important developments that have taken place at the Evogene group: namely, the strategic collaboration and $10 million investment by ICL, a leading global specialty minerals company, into our subsidiary, Lavie Bio; as well as the launch of the Phase I first in human clinical trial, by our subsidiary, Biomica.”
 
“The strategic collaboration between ICL and Lavie Bio and $10 million investment, combines Lavie Bio's ag-biologicals expertise, built on Evogene’s Microboost AI tech engine, with ICL's fertilizer experience, enabling the development of a pipeline of innovative bio-stimulant products for agriculture. Especially in a time of food scarcity, high prices, and macroeconomic uncertainty, Lavie Bio and ICL’s shared vision is to enhance global food quality, agricultural sustainability, and increased productivity. ICL will join Corteva, a major U.S. agricultural chemical and seed company, as well as Evogene, as a new shareholder of Lavie Bio and I am very proud that these two agricultural giants have a strong interest in what Evogene has built.”

“From Evogene's standpoint, this investment in our subsidiary Lavie Bio, is an additional key milestone that demonstrates the power of our business model, whereby we are leveraging the value of our tech engines through dedicated subsidiaries. It shows that our hard work in building, investing in and strengthening our subsidiaries, all of which are leveraging our underlying computational predictive biological tech engines, is the right strategy and bears fruit. ”
 
Continued Mr. Haviv, “The second important development was the launch by Biomica of its phase I clinical trial and the announcement that the first patient was dosed in its Phase I clinical trial for its microbiome-based immuno-oncology drug candidate, BMC128. The drug candidate is a consortium of microbes, which Biomica selected through a microbiome analysis via our MicroBoost AI tech engine. ”
 
“While Evogene has traditionally leveraged its platform and AI technology engines towards agriculture, Biomica is proof that we are uniquely positioned to play an important role in human health and is strong validation that our technology can be leveraged across multiple and massive industries.”
 

“Finally, we continued to strengthen our management team, recently adding Eyal Ronen as Executive Vice President of Business Development bringing us over 20 years of extensive business development experience with biotech companies. Eyal's focus is to create and bring us additional value by building new partnerships or forming new subsidiaries, leveraging our technology engines and expanding our activities into new areas. I strongly believe that Evogene has significant untapped potential in its technology engines, and Eyal will focus on realizing some of that value.”

Mr. Haviv added, “Evogene today is at a key inflection point, whereby we are meeting critical milestones and the inherent value of our subsidiaries is becoming increasingly obvious. Evogene's goal in the near term is to continue to bring high value-adding partners and investors at the subsidiary level, who understand and can value the potential from the products that our subsidiaries are developing. This we believe will demonstrate in a very public way, the significant untapped value contained within our activities. ”

“Our target is that each subsidiary will have its own financial resources to support its activities until its success, while we at Evogene, in addition to being a major shareholder, continue to play a major role in maintaining and building their competitive advantage through our tech-engines. ”

“In parallel, we are targeting and exploring the potential to establish new activities that can benefit from our technology. This is the main mission of our new EVP of Business Development, Eyal Ronen, and we are already starting to see some of his positive impact. ” concluded Mr. Haviv.

Consolidated Financial Results Summary
 
Cash position: Evogene continues to maintain a solid financial position for its activities with approximately $35.3 million in consolidated cash, cash related accounts and marketable securities as of June 30, 2022.  Approximately $3.6 million of Evogene’s consolidated cash is appropriated to its subsidiary, Lavie Bio. The Company does not have bank debt. It is noted that these amounts do not include the recent $10 million investment of ICL in Lavie Bio, which was fully received in August 2022 and will be reflected in the financial statements of the Company for the third quarter.

During the second quarter of 2022, the consolidated cash usage was approximately $9.3 million, or approximately $6.4 million, excluding Lavie Bio. Out of the $9.3 million, $1.7 million is a non-cash charge related to foreign exchange expenses due to US Dollar and New Israeli Shekel exchange rate differences and a decrease in the market value of marketable securities on Evogene’s balance sheet.


As previously stated, Evogene’s full year net cash burn rate, excluding exchange rate impacts in 2022, is expected to be in the range of $26-28 million including Lavie Bio and $18-20 million excluding Lavie Bio, which manages its own cash position.

Revenues: Revenues for the second quarter were $312 thousand, in comparison to $135 thousand in the same period the previous year. Revenues were primarily due to the initial sales of Lavie Bio’s Thrivus product (previously branded as Result) and sales of Canonic products in the Israeli market.

R&D expenses for the quarter, which are reported net of non-refundable grants received, were $5.4 million, in comparison to $5.0 million in the same period the previous year. The increase in R&D expenses was primarily due to:


1.
Biomica’s ongoing phase I trial of its first-in-human proof-of-concept study in its immuno-oncology program; and
 

2.
Lavie Bio's activities supporting the production and commercialization of its inoculant product.
 
Business Development expenses were approximately $1.0 million for the second quarter of 2022, in comparison to $0.7 million in the same period the previous year. The increase in the Business Development expenses was primarily due to recruitment of business development personnel supporting the commercialization activities of Evogene’s subsidiaries.

General and Administrative expenses remained stable, and for the second quarter of 2022 were $1.7 million, in comparison to $1.8 million in the same period in the previous year.

Operating loss: Operating loss for the second quarter of 2022 was $8.0 million in comparison to $7.4 million in the same period in the previous year.
 
Financing expenses for the second quarter of 2022 were $1.7 million, in comparison to financing income of $0.6 million in the same period in the previous year. The increase in financing expenses was mainly due to the U.S. Dollar and New Israeli Shekel exchange rate differences between periods and a decrease in marketable securities value as mentioned above.
 
Net loss: The net loss for the second quarter of 2022 was $9.8 million, in comparison to a net loss of $6.9 million in the same period in the previous year. The increase in net loss was mainly due to the financing expenses as described above.
 
***


Conference Call & Webcast Details:
 
Date: August 31, 2022
 
Time: 9:00 am ET; 16:00 Israel time
 
Dial-in numbers:1-888-281-1167 toll free from the United States, or +972-3-918-0609 internationally
 
Webcast & Presentation link available at:
 
https://www.evogene.com/investor-relations/presentations-and-webcasts/
 
The Company's investors presentation can be viewed at the above link, which is in the investor relations section of the company website.
 
Replay Information: A replay of the conference call will be available approximately two hours following the completion of the call.
 
To access the replay, please dial 1-888-326-9310 toll free from the United States, or +972-3-925-5901 internationally. The replay will be accessible following the call for three days. An archive of the webcast will be available on the Company’s website.
 

About Evogene Ltd.:
 
Evogene (NASDAQ: EVGN, TASE: EVGN) is a computational biology company aiming to revolutionize the development of life-science based products by utilizing cutting edge technologies to increase probability of success while reducing development time and cost. Evogene established three unique technological engines – MicroBoost AI, ChemPass AI and GeneRator AI – leveraging Big Data and Artificial Intelligence and incorporating deep multidisciplinary understanding in life sciences. Each technological engine is focused on the discovery and development of products based on one of the following core components: microbes (MicroBoost AI), small molecules (ChemPass AI), and genetic elements (GeneRator AI). Evogene uses its technological engines to develop products through subsidiaries and with strategic partners. Currently, Evogene’s main subsidiaries utilize the technological engines to develop human microbiome-based therapeutics by Biomica Ltd., medical cannabis products by Canonic Ltd., ag-chemicals by Ag Plenus Ltd. and ag-biologicals by Lavie Bio Ltd.  For more information, please visit: www.evogene.com.
 
 Forward Looking Statements
 
This press release contains "forward-looking statements" relating to future events. These statements may be identified by words such as may”, “could”, “expects”, “hopes” “intends”, “anticipates”, “plans”, “believes”, “scheduled”, “estimates” or words of similar meaning. For example, Evogene is using forward-looking statement in this press release when it discusses its expectations with respect to value creation and potential funding options, including through its subsidiaries, untapped potential and value, including the potential to establish new activities that can benefit from Evogene’s technology, its and its subsidiaries’ expected trials, studies, product advancements, pipelines, commercializations, collaborations, sales, launches, milestones, target markets, cash usage and other plans for 2022 and on, and the potential advantages of its technology. Such statements are based on current expectations, estimates, projections and assumptions, describe opinions about future events, involve certain risks and uncertainties which are difficult to predict and are not guarantees of future performance. Therefore, actual future results, performance or achievements of Evogene and its subsidiaries may differ materially from what is expressed or implied by such forward-looking statements due to a variety of factors, many of which are beyond the control of Evogene and its subsidiaries, including, without limitation, those risk factors contained in Evogene’s reports filed with the applicable securities authority. In addition, Evogene and its subsidiaries rely, and expect to continue to rely, on third parties to conduct certain activities, such as their field-trials and pre-clinical studies, and if these third parties do not successfully carry out their contractual duties, comply with regulatory requirements or meet expected deadlines, Evogene and its subsidiaries may experience significant delays in the conduct of their activities. Evogene and its subsidiaries disclaim any obligation or commitment to update these forward-looking statements to reflect future events or developments or changes in expectations, estimates, projections and assumptions.
 
Evogene Investor Contact:
 
Kenny Green
Email: ir@evogene.com
Tel: +1 212 378 8040
 


CONSOLIDATED STATEMENTS OF FINANCIAL POSITION
U.S. dollars in thousands

   
June 30,
   
December 31,
 
   
2022
   
2021
 
   
Unaudited
   
Audited
 
CURRENT ASSETS:
           
Cash and cash equivalents
 
$
28,867
   
$
32,325
 
Short-term bank deposits
   
-
     
3,000
 
Marketable securities
   
6,383
     
18,541
 
Trade receivables
   
111
     
281
 
Inventories
   
162
     
92
 
Other receivables and prepaid expenses
   
2,182
     
2,651
 
                 
     
37,705
     
56,890
 
LONG-TERM ASSETS:
               
Long-term deposits
   
24
     
25
 
Right-of-use-assets
   
1,808
     
2,109
 
Property, plant and equipment, net
   
2,495
     
2,073
 
Intangible assets, net
   
14,630
     
15,207
 
                 
     
18,957
     
19,414
 
                 
   
$
56,662
   
$
76,304
 
CURRENT LIABILITIES:
               
Trade payables
 
$
1,324
   
$
1,463
 
Employees and payroll accruals
   
2,384
     
2,662
 
Lease liability
   
754
     
974
 
Liabilities in respect of government grants
   
126
     
89
 
Deferred revenues and other advances
   
16
     
175
 
Other payables
   
937
     
1,519
 
                 
     
5,541
     
6,882
 
LONG-TERM LIABILITIES:
               
Lease liability
   
1,367
     
1,695
 
Liabilities in respect of government grants
   
4,357
     
4,307
 
                 
     
5,724
     
6,002
 
SHAREHOLDERS' EQUITY:
               
Ordinary shares of NIS 0.02 par value:
Authorized − 150,000,000 ordinary shares; Issued and outstanding – 41,202,018 shares as of June 30, 2022 and 41,170,168  shares as of December 31, 2021
   
234
     
234
 
Share premium and other capital reserve
   
260,880
     
260,488
 
Accumulated deficit
   
(224,165
)
   
(207,069
)
                 
Equity attributable to equity holders of the Company
   
36,949
     
53,653
 
                 
Non-controlling interests
   
8,448
     
9,767
 
                 
   Total equity
   
45,397
     
63,420
 
                 
   
$
56,662
   
$
76,304
 


CONSOLIDATED STATEMENTS OF PROFIT OR LOSS
U.S. dollars in thousands

   
Six months ended
June 30,
   
Three months ended
June 30,
   
Year ended December 31,
 
   
2022
   
2021
   
2022
   
2021
   
2021
 
   
Unaudited
   
Audited
 
                               
Revenues
 
$
549
   
$
468
   
$
312
   
$
135
   
$
930
 
Cost of revenues
   
425
     
399
     
262
     
128
     
767
 
                                         
Gross profit
   
124
     
69
     
50
     
7
     
163
 
                                         
Operating expenses:
                                       
                                         
Research and development, net
   
11,043
     
9,283
     
5,417
     
4,986
     
21,125
 
Business development
   
1,870
     
1,242
     
962
     
672
     
2,738
 
General and administrative
   
3,273
     
3,249
     
1,678
     
1,795
     
7,253
 
                                         
Total operating expenses
   
16,186
     
13,774
     
8,057
     
7,453
     
31,116
 
                                         
Operating loss
   
(16,062
)
   
(13,705
)
   
(8,007
)
   
(7,446
)
   
(30,953
)
                                         
Financing income
   
485
     
617
     
444
     
565
     
1,935
 
Financing expenses
   
(3,243
)
   
(919
)
   
(2,153
)
   
(14
)
   
(1,414
)
                                         
Financing income (expenses), net
   
(2,758
)
   
(302
)
   
(1,709
)
   
551
     
521
 
                                         
Loss before taxes on income
   
(18,820
)
   
(14,007
)
   
(9,716
)
   
(6,895
)
   
(30,432
)
Taxes on income
   
40
     
11
     
38
     
3
     
13
 
                                         
Loss
 
$
(18,860
)
 
$
(14,018
)
 
$
(9,754
)
 
$
(6,898
)
 
$
(30,445
)
                                         
Attributable to:
                                       
Equity holders of the Company
 
$
(17,096
)
   
(12,812
)
   
(8,821
)
   
(6,210
)
   
(27,793
)
Non-controlling interests
   
(1,764
)
   
(1,206
)
   
(933
)
   
(688
)
   
(2,652
)
                                         
   
$
(18,860
)
 
$
(14,018
)
 
$
(9,754
)
 
$
(6,898
)
 
$
(30,445
)
                                         
Basic and diluted loss per share, attributable to equity holders of the Company
 
$
(0.42
)
 
$
(0.32
)
 
$
(0.21
)
 
$
(0.15
)
 
$
(0.69
)
                                         
Weighted average number of shares used in computing basic and diluted loss per share
   
41,195,024
     
39,778,174
     
41,202,018
     
40,580,563
     
40,433,303
 


CONSOLIDATED STATEMENTS OF CASH FLOWS

U.S. dollars in thousands

   
Six months ended
June 30,
   
Three months ended
June 30,
   
Year ended December 31,
 
   
2022
   
2021
   
2022
   
2021
   
2021
 
   
Unaudited
   
Audited
 
    Cash flows from operating activities
                             
                               
   Loss
 
$
(18,860
)
 
$
(14,018
)
 
$
(9,754
)
 
$
(6,898
)
 
$
(30,445
)
                                         
Adjustments to reconcile loss to net cash used in operating activities:
                                       
                                         
Adjustments to the profit or loss items:
                                       
                                         
Depreciation
   
717
     
672
     
371
     
342
     
1,302
 
Amortization of intangible assets
   
577
     
462
     
242
     
232
     
932
 
Share-based compensation
   
830
     
1,089
     
419
     
558
     
2,609
 
Net financing expenses (income)
   
3,139
     
(7
)
   
2,033
     
(893
)
   
(884
)
Increase (decrease) in accrued bank interest
   
7
     
-
     
-
     
(12
)
   
11
 
Pre-funded warrants issuance expenses
   
-
     
212
     
-
     
212
     
-
 
Loss from derecognition of property, plant and equipment
   
-
     
-
     
-
     
-
     
121
 
Taxes on income
   
40
     
11
     
38
     
3
     
13
 
                                         
     
5,310
     
2,439
     
3,103
     
442
     
4,104
 
Changes in asset and liability items:
                                       
                                         
Decrease (increase) in trade receivables
   
170
     
14
     
55
     
11
     
(59
)
Decrease in other receivables
   
463
     
1,007
     
551
     
289
     
637
 
Decrease (increase) in inventories
   
(70
)
   
-
     
10
     
-
     
(92
)
Increase (decrease) in trade payables
   
(172
)
   
355
     
(6
)
   
232
     
625
 
Increase (decrease) in employees and payroll accruals
   
(278
)
   
(318
)
   
(272
)
   
(180
)
   
127
 
Increase (decrease) in other payables
   
(593
)
   
(278
)
   
(147
)
   
(23
)
   
290
 
Increase (decrease) in deferred revenues and other advances
   
(159
)
   
(21
)
   
(99
)
   
-
     
128
 
                                         
     
(639
)
   
759
     
92
     
329
     
1,656
 
                                         
Cash received (paid) during the period for:
                                       
                                         
Interest received
   
80
     
145
     
31
     
76
     
297
 
Interest paid
   
(227
)
   
(138
)
   
(103
)
   
(81
)
   
(315
)
Taxes paid
   
(29
)
   
(11
)
   
(27
)
   
(3
)
   
(13
)
                                         
Net cash used in operating activities
 
$
(14,365
)
 
$
(10,824
)
 
$
(6,658
)
 
$
(6,135
)
 
$
(24,716
)


CONSOLIDATED STATEMENTS OF CASH FLOWS

U.S. dollars in thousands

   
Six months ended
June 30,
   
Three months ended
June 30,
   
Year ended December 31,
 
   
2022
   
2021
   
2022
   
2021
   
2021
 
   
Unaudited
   
Audited
 
Cash flows from investing activities:
                             
                               
Purchase of property, plant and equipment
   
(747
)
   
(407
)
   
(305
)
   
(224
)
   
(847
)
Proceeds from sale of marketable securities
   
12,149
     
406
     
2,725
     
205
     
4,395
 
Purchase of marketable securities
   
(659
)
   
(20,990
)
   
(659
)
   
(709
)
   
(23,114
)
Withdrawal from (investment in) bank deposits
   
3,000
     
-
     
-
     
9,500
     
(1,000
)
                                         
Net cash provided by (used in) investing activities
 
$
13,743
   
$
(20,991
)
 
$
1,761
   
$
8,772
   
$
(20,566
)
                                         
Cash flows from financing activities:
                                       
                                         
Proceeds from issuance of ordinary shares, net of issuance expenses
   
-
     
27,922
     
-
     
814
     
29,582
 
Proceeds from exercise of options
   
7
     
460
     
-
     
15
     
484
 
Repayment of lease liability
   
(492
)
   
(316
)
   
(369
)
   
(149
)
   
(580
)
Proceeds from government grants
   
30
     
380
     
-
     
257
     
824
 
Repayment of government grants
   
(14
)
   
(20
)
   
-
     
-
     
(34
)
                                         
Net cash provided by (used in) financing activities
   
(469
)
   
28,426
     
(369
)
   
937
     
30,276
 
                                         
Exchange rate differences - cash and cash equivalent balances
   
(2,367
)
   
(85
)
   
(1,880
)
   
539
     
1,102
 
                                         
Increase (decrease) in cash and cash equivalents
   
(3,458
)
   
(3,474
)
   
(7,146
)
   
4,113
     
(13,904
)
                                         
Cash and cash equivalents, beginning of the period
   
32,325
     
46,229
     
36,013
     
38,642
     
46,229
 
                                         
Cash and cash equivalents, end of the period
 
$
28,867
   
$
42,755
   
$
28,867
   
$
42,755
   
$
32,325
 
                                         
Significant non-cash activities
                                       
Acquisition of property, plant and equipment
 
$
66
   
$
42
   
$
66
   
$
42
   
$
32
 
                                         
Increase of right-of-use asset recognized with corresponding lease liability
 
$
30
   
$
317
   
$
-
   
$
155
   
$
841
 
Exercise of pre-funded warrants
   
-
     
4,365
     
-
     
-
   
$
4,365