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Share-based compensation - Share options outstanding (Details) - Share option plans - Options
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Share-based compensation        
Outstanding share options 5,540,600 5,128,680 2,661,096 779,813
Not later than one year        
Share-based compensation        
Outstanding share options 49,687 555,126    
Later than one year and not later than two years        
Share-based compensation        
Outstanding share options 155,000 49,687 555,126  
Later than two years and not later than three years        
Share-based compensation        
Outstanding share options   155,000 49,687  
Later than three years and not later than four years        
Share-based compensation        
Outstanding share options     155,000  
Later than four years and not later than five years        
Share-based compensation        
Outstanding share options 506,351      
Later than seven years and not later than eight years        
Share-based compensation        
Outstanding share options 1,901,283      
Later than eight years and not later than nine years        
Share-based compensation        
Outstanding share options 2,711,090 1,901,283    
Later than nine years and not later than ten years        
Share-based compensation        
Outstanding share options 217,189 2,467,584 1,901,283  
Exercise Price CHF1.00        
Share-based compensation        
Outstanding share options 292,261 292,261 292,261  
Exercise Price CHF1.00 | Later than seven years and not later than eight years        
Share-based compensation        
Outstanding share options 292,261      
Exercise Price CHF1.00 | Later than eight years and not later than nine years        
Share-based compensation        
Outstanding share options   292,261    
Exercise Price CHF1.00 | Later than nine years and not later than ten years        
Share-based compensation        
Outstanding share options     292,261  
Exercise Price CHF1.50        
Share-based compensation        
Outstanding share options 187,189      
Exercise Price CHF1.50 | Later than nine years and not later than ten years        
Share-based compensation        
Outstanding share options 187,189      
Exercise Price CHF1.80        
Share-based compensation        
Outstanding share options 30,000      
Exercise Price CHF1.80 | Later than nine years and not later than ten years        
Share-based compensation        
Outstanding share options 30,000      
Exercise Price CHF2.00        
Share-based compensation        
Outstanding share options 2,270,060 2,318,835 2,318,835  
Exercise Price CHF2.00 | Not later than one year        
Share-based compensation        
Outstanding share options 49,687 555,126    
Exercise Price CHF2.00 | Later than one year and not later than two years        
Share-based compensation        
Outstanding share options 105,000 49,687 555,126  
Exercise Price CHF2.00 | Later than two years and not later than three years        
Share-based compensation        
Outstanding share options   105,000 49,687  
Exercise Price CHF2.00 | Later than three years and not later than four years        
Share-based compensation        
Outstanding share options     105,000  
Exercise Price CHF2.00 | Later than four years and not later than five years        
Share-based compensation        
Outstanding share options 506,351      
Exercise Price CHF2.00 | Later than seven years and not later than eight years        
Share-based compensation        
Outstanding share options 1,609,022      
Exercise Price CHF2.00 | Later than eight years and not later than nine years        
Share-based compensation        
Outstanding share options   1,609,022    
Exercise Price CHF2.00 | Later than nine years and not later than ten years        
Share-based compensation        
Outstanding share options     1,609,022  
Exercise Price CHF2.08        
Share-based compensation        
Outstanding share options 50,000 50,000 50,000  
Exercise Price CHF2.08 | Later than one year and not later than two years        
Share-based compensation        
Outstanding share options 50,000      
Exercise Price CHF2.08 | Later than two years and not later than three years        
Share-based compensation        
Outstanding share options   50,000    
Exercise Price CHF2.08 | Later than three years and not later than four years        
Share-based compensation        
Outstanding share options     50,000  
Exercise Price CHF2.25        
Share-based compensation        
Outstanding share options 243,506      
Exercise Price CHF2.25 | Later than eight years and not later than nine years        
Share-based compensation        
Outstanding share options 243,506      
Exercise Price CHF3.00        
Share-based compensation        
Outstanding share options 2,467,584 2,467,584    
Exercise Price CHF3.00 | Later than eight years and not later than nine years        
Share-based compensation        
Outstanding share options 2,467,584      
Exercise Price CHF3.00 | Later than nine years and not later than ten years        
Share-based compensation        
Outstanding share options   2,467,584