X0306 4 2017-05-30 0 0001638287 Gemphire Therapeutics Inc. GEMP 0001571997 Gullans Steven R. Ph.D. 17199 N. LAUREL PARK DRIVE SUITE 401 LIVONIA MI 48152 1 1 0 0 Interim President & CEO Employee Stock Option (right to buy) 10.26 2017-05-30 4 A 0 60000 0 A 2027-05-29 Common Stock 60000 60000 D The option vests in 12 equal consecutive monthly increments, so that all of the shares will be vested on the one year anniversary of the date of grant, subject to acceleration upon the appointment of a permanent President and Chief Executive Officer. Stephanie Swan, by Power of Attorney 2017-05-31