X0306 4 2017-03-10 0 0001638287 Gemphire Therapeutics Inc. GEMP 0001571997 Gullans Steven R. Ph.D. 17199 N. LAUREL PARK DRIVE SUITE 401 LIVONIA MI 48152 1 0 0 0 Common Stock 2017-03-10 4 P 0 52798 9.47 A 858823 I Held by Excel Venture Fund II, L.P. Warrant to Purchase Common Stock 10.4 2017-03-10 4 P 0 39599 9.47 A 2017-03-10 2022-03-15 Common Stock 39599 39599 I Held by Excel Venture Fund II, L.P. The shares of common stock and warrants were purchased as part of a private placement pursuant to a Securities Purchase Agreement whereby the Issuer sold units consisting of one share of the Issuer's common stock and a warrant to purchase 0.75 shares of the Issuer's common stock at a per unit price of $9.47. The private placement is expected to close on March 15, 2017. The reporting person, as the Manager of Excel Venture Fund II, L.P., beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. Stephanie Swan, by Power of Attorney 2017-03-14