X0306 4 2021-11-08 0 0001571949 Intercontinental Exchange, Inc. ICE 0001722067 Jackson Benjamin 5660 NEW NORTHSIDE DRIVE ATLANTA GA 30328 0 1 0 0 President Common Stock 2021-11-08 4 M 0 2770 41.37 A 99583 D Employee Stock Option (right to buy) Holding 41.37 2021-11-08 4 M 0 2770 0.00 D 2024-01-17 Common Stock 2770 22100 D The transactions reported in this Form 4 were effected pursuant to a pre-arranged trading plan established in accordance with Rule 10b5-1 of the Securities Act of 1934, as amended. Amount of securities beneficially owned includes 110 shares acquired under the Intercontinental Exchange, Inc. Employee Stock Purchase Plan on June 30, 2021. The common stock number referred in Table I is an aggregate number and represents 81,291 shares of common stock and 18,292 unvested performance based restricted stock units, for which the performance period has been satisfied. These performance based restricted stock units vest over a three year period, in which 33.33% of the units vest each year. The satisfaction of the 2021 performance based restricted units tied to earnings before interest, taxes, depreciation, and amortization ("EBITDA") and the corresponding number of shares to be issued pursuant to these awards, will not be determined until February 2022 and will be reported at the time of vesting. The satisfaction of the 2019, 2020 and 2021 total shareholder return performance based restricted stock units and the corresponding number of shares to be issued pursuant to these awards, will not be determined until February 2022, February 2023 and February 2024, respectively, and will be reported at the time of vesting. These options are fully vested. /s/ Octavia N. Spencer, Attorney-in-fact 2021-11-10