Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2022	Dec. 31, 2020
Accounting Policies [Line Items]
Cost of revenue	$ 2,637	$ 2,853
Amortization of Intangible Assets	1,000	1,000
Estimated future amortization of intangible assets			$ 3,200
Estimated future amortization of intangible assets thereafter			$ 4,200
Tazemetostat Drug Pruducts [Member]
Accounting Policies [Line Items]
Cost of revenue	$ 0	$ 800
Eisai [Member]
Accounting Policies [Line Items]
Milestone payments				$ 50,000