Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenue:
Total revenue	$ 8,696	$ 7,631
Operating expenses:
Cost of revenue	2,637	2,853
Research and development	29,781	32,704
Selling, general and administrative	27,204	36,411
Total operating expenses	59,622	71,968
Operating loss	(50,926)	(64,337)
Other (expense) income, net:
Interest expense , net	(5,480)	(5,476)
Other expense (income), net	(48)	9
Change in fair value of warrants to purchase common stock	1,350	0
Related party non-cash interest expense related to sale of future royalties	(370)	(470)
Other expense, net	(4,548)	(5,937)
Loss before income taxes	(55,474)	(70,274)
Income tax provision	(31)	0
Net loss	(55,505)	(70,274)
Other comprehensive income (loss):
Unrealized (loss) gain on available-for-sale securities	(194)	3
Comprehensive loss	$ (55,699)	$ (70,271)
Net loss per share attributable to common stockholders:
Basic	$ (0.38)	$ (0.69)
Diluted	$ (0.38)	$ (0.69)
Weighted-average common shares outstanding used in net loss per share attributable to common stockholders:
Basic	144,201	101,790
Diluted	144,201	101,790
Product [Member]
Revenue:
Total revenue	$ 8,656	$ 6,191
Collaboration and Other Revenue [Member]
Revenue:
Collaboration and other revenue	$ 40	$ 1,440