EXHIBIT 99.1

Joint Filing Agreement

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing statements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him, her or it contained herein, but shall not be responsible for the completeness and accuracy of the information concerning the other entities or persons, except to the extent that he, she or it knows or has reason to believe that such information is inaccurate.

Dated: February 14, 2022

THIRD ROCK VENTURES III, L.P.
By: THIRD ROCK VENTURES GP III, L.P.,
General Partner
By: TRV GP III, LLC,
General Partner
By:	/s/ Kevin Gillis
Kevin Gillis
Chief Operating Officer
THIRD ROCK VENTURES GP III, L.P.
By: TRV GP III, LLC,
General Partner
By:	/s/ Kevin Gillis
Kevin Gillis
Chief Operating Officer
TRV GP III, LLC
By:	/s/ Kevin Gillis
Kevin Gillis
Chief Operating Officer
THIRD ROCK VENTURES IV, L.P.
By: THIRD ROCK VENTURES GP IV, L.P.,
General Partner
By: TRV GP IV, LLC,
General Partner
By:	/s/ Kevin Gillis
Kevin Gillis

Chief Operating Officer
THIRD ROCK VENTURES GP IV, L.P.
By: TRV GP IV, LLC,
General Partner
By:	/s/ Kevin Gillis
Kevin Gillis
Chief Operating Officer
TRV GP IV, LLC
By:	/s/ Kevin Gillis
Kevin Gillis
Chief Operating Officer
MARK LEVIN
/s/ Kevin Gillis, As attorney-in-fact
Mark Levin
KEVIN P. STARR
/s/ Kevin Gillis, As attorney-in-fact
Kevin P. Starr
ROBERT I. TEPPER
/s/ Kevin Gillis, As attorney-in-fact
Robert I. Tepper