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General (Details)
12 Months Ended
Dec. 31, 2021
Disclosure of general information about financial statements [text block] [Abstract]  
Agreement on initiation of sales, description Commencing 2022, Takeda will pay royalties to the Company at a rate of 12% on GLASSIA’s net sales through August 2025, and at a rate of 6% thereafter until 2040, with a minimum of $5 million annually.
Operating segment, description The Company’s activity is divided into two operating segments: 
Subsidiary ownership interest, percentage 74.00%